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Research Assistant | Western Psychiatric Hospital

Description

Our laboratory studies the biochemical and molecular bases of neurodegenerative pathologies in Alzheimer and non-Alzheimer tauopathies, in the human brain and biofluids. Our group applies this knowledge to develop and validate novel biomarkers for clinical and research use, employing highly sensitive mass spectrometric and immunoassay technologies. We focus on developing and evaluating blood and cerebrospinal fluid (CSF) biomarkers that: (i) become abnormal very early in Alzheimer’s disease (AD), enabling diagnosis at the preclinical and prodromal stages; (ii) associate with neuropathological confirmation and predict longitudinal changes; (iii) reflect different aspects of AD pathophysiology (e.g., amyloid, tau, neurodegeneration, glia activation, inflammation and synaptic dysfunction); and (iv) predict future functional and cognitive changes.  

In recent years, we have discovered novel forms of phosphorylated tau in blood and CSF, and have developed and verified new diagnostic tools (some now commercialized and others patented) to quantify these as AD biomarkers suitable for clinical use. These biomarkers have now been validated in dozens of research cohorts and are now widely used for therapeutic trials, diagnosis, prognosis and research studies. 

The Research Assistant will perform biomarker analyses in biospecimens from research and clinical participants, following clearly laid out standards of practice, overseen by the PI.  They will also process these data and prepare reports for the collaborating studies.

This position is grant funded.

Responsibilities:

  • Organize references and materials for research projects and content areas.
  • Maintain professionalism in all interactions with stakeholders and internal staff.
  • Conduct literature searches.
  • Provide support for grant proposal and manuscript development and submission.
  • Participate in meetings, trainings and seminars, both internally and externally.
  • Perform data collection and entry.
  • Assist in data management.

Qualifications

  • Bachelor's or Master's degree in a related field, or current enrollment, with some experience in research environment.
  • Experience in the area of public health, psychology, applied research or behavioral health is preferred. Strong written and verbal skills.
  • Detail oriented.
  • Proficiency with Microsoft Word, Excel, Access and the ability to learn various software packages as needed.

Licensure, Certifications, and Clearances:

  • Act 34

UPMC is an Equal Opportunity Employer/Disability/Veteran

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