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Lead Molecular Genomic Specialist

  • Job ID: 083084459
  • Status: Full-Time
  • Regular/Temporary: Regular
  • Hours: Daylight, M-F
  • Shift: Day Job
  • Facility: UPMC Presbyterian
  • Department: Molecular Gen Path
  • Location: 200 Lothrop St, Pittsburgh PA 15213
  • Union Position: No
  • Salary Range: $23.75 to $41.09 / hour


UPMC Presbyterian is hiring a full-time Lead Molecular Genomic Specialist to support the Molecular and Genomic Pathology (MGP) Laboratory! This role will be scheduled daylight shift, Monday-Friday.

The MGP Lab is a dynamic, state-of-the-art clinical laboratory that prides itself on delivering the highest quality of patient care in the fields of inherited diseases, hematological malignancies, and solid tumors by utilizing cutting-edge molecular testing platforms and informatics approaches exemplified by next-generation sequencing. This role offers a challenging and rewarding career by providing a wide variety of job responsibilities as well as opportunities to identify and build upon individual strengths. Additionally, the MGP Lab promotes lab-wide collaboration and teamwork where each staff member is valued for their unique skill set that they can offer to the team.

UPMC is Pennsylvania’s largest nongovernmental employer with endless opportunities. We offer a competitive benefits package that few employers can match and have a career ladder in place that provides growth opportunities for lab associates to enjoy more professional challenges, promotional opportunities and career enhancement! Apply today to find out where your career can take you!


Provide direct support for Molecular Genomic Supervisor by monitoring complex molecular work of technical staff. The Lead Molecular Genomic Specialist assists in test development, gathers data for management reports and regularly performs the duties of Molecular Genomic Specialists including the accurate performance of advanced clinical molecular testing. This position functions as the Molecular Genomic Supervisor during the Supervisor's absence.

  • Act as point-person for communication with vendors regarding problems with instruments and/or software.
  • Update SOPs, as needed, to maintain current accurate procedure documentation.
  • Monitor personnel and workflow in area.
  • Track and monitor QA/QC in conjunction with other laboratory leadership. 
  • Maintain all QA documentation for area including tracking reagent lot numbers, in/out of use dates, expiration date, etc., Exception Log with corrective action follow-up and QA reports.
  • Maintain track of technical and professional development, including but not limited to attendance at seminars/webinars and participation in educational programs and activities.
  • Track area technologist indirect hours (MRS).
  • Work with laboratory leadership including Medical Director for ideas for, validation of and implementation of development projects.
  • Monitor and approve reagent/supply orders for area.
  • Act as liaison for daily happenings in clinical workflow between technologists and laboratory leadership.
  • Perform clinical testing in accordance with established SOPs.
  • Maintain oversight of all clinical testing. 
  • Maintain clinical workflow for area to meet established quality and TAT, including technologist and bench schedule, status of cases (STAT, special request, etc).
  • Maintain competency for all benches in area. 
  • Rotate regularly through clinical workflow. 
  • Be able to step in and help clinical work when necessary.
  • Troubleshoot problematic cases, including when to repeat case and when to cancel testing.
  • With support and guidance from laboratory leadership and Medical Director, oversee supplemental validations and implementation of procedural changes. 
  • Write-up all supplemental validations and compile supporting data.
  • Oversee training of technologists, including new hires and cross training of current technologists.
  • Work with MGP QA and lab leadership and Medical Director as needed for preparation for inspections.
  • Complete performance reviews for all area Molecular Genomic Specialists.
  • Monitor and assess competency for all area technologists. 
  • Adhere to CAP and other regulatory agency regulations for competency assessment.
  • Monitor Proficiency Testing for assays in area. 
  • Track all results for concordance and document as appropriate.
  • Prepares multiple and various routine and non-routine clinical laboratory procedures manually or by utilizing automated and semi-automated equipment including highly sophisticated testing devices.
  • Calculates and analyzes assay/test results and quality control information utilizing all relevant information including patient histories, formulas or calculations, or computerized data processing. 
  • Investigates abnormal results.
  • Develop and supervise new advanced state of the art diagnostic platforms for molecular anatomic pathology clinical testing.
  • Maintains detailed laboratory documentation of all experiments performed and related data and submits written reports of test results.
  • Write standard operating procedures and validations studies.
  • Collects background information for testing/experiments; performs test set-up; prepares instrument work area, and equipment; ensures validity of test specimens.
  • Implements all quality controls to ensure test validity; adheres to departmental safety standards in responsibly handling, processing and testing specimens and materials. 
  • Maintains (as possible), calibrates and cleans equipment; verifies proper function.
  • Participates in the design and methodology of research and development projects, including how resultant data would best be analyzed.
  • Trains laboratory staff on newly developed clinical tests and performs follow-up quality assurance (Q/A) activities.
  • Primary responsibility for technical oversight/guidance of the Molecular Anatomic Pathology Development Platform. 
  • Activities to include development of new and novel testing modalities, maintenance of technical excellence, compliance with regulatory, safe.
  • Primary responsibility for development of Affymetrix array platform.


  • BS degree in biological science field OR;
  • BS degree in chemical or physical science field with 16 semester hours in chemistry (including at least 6 hours in inorganic chemistry), 16 semester hours in biology courses pertinent to the medical sciences, and 3 semester hours in mathematics.
  • At least 4 years of experience in a clinical molecular laboratory.
  • Prior leadership experience preferred.
Licensure, Certifications, and Clearances:
  • (MB) ASCP certification preferred.
  • Act 34
UPMC is an Equal Opportunity Employer/Disability/Veteran

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   Current UPMC employees must apply in HR Direct