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Research Principal

Description

Purpose:
The D’Aiuto/Nimgaonkar Laboratory is part of the Program for Genetics and Psychosis at Western Psychiatric Hospital of UPMC. Our laboratory is high-energy environment that focuses on the modeling of viral infections in the central nervous system using induced pluripotent stem cells. We have a history of innovative and impactful research in the field of psychiatry, genetics and virology. 

This position is grant funded.

Responsibilities:
  • Provide advanced level research and/or clinical and administrative support for the research study.
  • Mentor, train, and assist with supervising junior research staff as needed.
Grant Funded Responsibilities:

  • Maintain induced pluripotent stem cell cultures (iPSC)

  • Differentiate iPSCs into different central nervous system cell types

  • Perform viral infections of iPSC-derived neuronal culture

  • Perform tissue sections, immunohistochemistry analyses, RT qPCR, in situ hybridization, Western Blotting, DNA cloning, DNA extraction and DNA variant analyses

  • Perform in silico analyses of public genomic and infectious disease databases

  • Maintain proper records of all laboratory tests, including data entry into computerized data bases.

  • Obtain and/or transport human tissue when required, as part of the research.

  • Maintain inventory of chemicals and laboratory ware. Order fresh supplies as required.

  • Disposal of laboratory wastes, as required.

  • Perform statistical analyses

  • Perform manuscript preparation and pursue publication of scientific correspondence.

  • Assist in preparation of grant applications

  • Perform in accordance with system-wide competencies/behaviors.

  • Perform other duties as assigned.

Qualifications

  • Masters degree required preferably in psychology, neuroscience, counseling, sociology, or related research field. Masters Degree in biology, microbiology, molecular genetics highly preferred.
  • Minimum of two years work experience in a research project and/or related clinical setting is required. Four years of laboratory research highly preferred.
  • Prior supervisory experience preferred.
  • Familiarity with computers and common software packages required.
  • Working knowledge of research methodology required.
Licensure, Certifications, and Clearances:
  • Act 34
UPMC is an Equal Opportunity Employer/Disability/Veteran

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