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Research Associate Basic Science

Description

UPMC Magee-Womens Hospital is seeking a Full-time Research Associate – Basic Science!

 

This position will work daylight hours. Hours are subject to change based on business needs.

Dr. Mahdi’s lab is focused on translational research in ovarian cancer and to less extend endometrial cancer. The main focus is tumor immune microenvironment and immune-oncology specifically myeloid cells and TGF-B and their role as immunosuppressive factors within the tumor immune microenvironment and impact of targeting them in combination approach in vivo and in-vitro. Further, another focus is targeted combination therapy focusing on HER2 and ATR based therapies. Lastly, new project started investigating the role of circulating tumor DNA in ovarian and other gynecologic cancer using ULP-WGS sequencing to estimate tumor fraction and inform the extent of next step of targeted sequencing.

 

This position is grant-funded.

 

Research in the lab focuses on the use of stem cells, gene therapy, and transplantation methods to treat infertility. This position will be responsible for managing a large animal colony to supply the research needs to the laboratory, process and analyze patient samples, perform molecular biology research, perform mouse embryo manipulation, and small animal surgery. 


Conducts and manages independent research, assists with grant applications and manuscript preparation, and trains research personnel.

Responsibilities:

  • Develop research projects including protocol design, budget preparation and justification, data collection and analysis, and data storage.
  • Effectively communicates progress of research projects via meetings with, and written reports to, research investigators.
  • Plan and implement training programs for Research Assistants on research activities and practice including grant application, budget management, data analysis, record keeping, and scientific integrity.
  • Maintain and expand research expertise by acquiring new research techniques and keeping abreast of new knowledge.
  • Responsible for following the mandatory reporting procedures for any incident or serious event that did affect or potentially could have affected the clinical care of any patient.
  • Assist in the preparation and submission of grant applications including budget preparation and justification. Obtain approval for research projects from review committees. Assist in manuscript preparation.
  • Conduct research in a manner that maintains and promotes scientific integrity and ensures that research projects and the environment comply with all applicable laws and regulations.
  • Supervise research assistants and monitors budgets. Responsible for record-keeping, inventory, and equipment management.

 

Qualifications

  • Master's degree in a basic science or clinical research area relevant to research activities to be performed with at least one-year experience; OR Bachelor degree in basic science with at least three years' experience working within a biomedical research environment, which would include coordinating and executing a research protocol including manuscript preparation.
  • Demonstrated ability to exercise independent judgment in the design and implementation of research projects.
  • Interpersonal skills necessary to manage and train research personnel, and to effectively communicate and interface with faculty and hospital staff.
  • Experience with cell culture, in-vitro and in-vivo studies, different assays like PCR, Western Blot, ELISA, DNA and RNA extraction preferred
  • Experience with immune assays like flow cytometry, cytokines, and immune analyses

 

Licensure, Certifications, and Clearances:

  • Act 34

UPMC is an equal opportunity employer. Minority/Females/Veterans/Individuals with Disabilities.

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   Current UPMC employees must apply in HR Direct

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