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Research Manager II

Description

UPMC Magee-Womens Hospital is seeking a Full-time Research Manager II to support the Research Operations department!

In Dr. Sadovsky’s lab, we study fetoplacental development, which is critical for long-term health and wellness. Using human placental cells, mouse models, and placental samples from normal and abnormal human pregnancies, we investigate molecular pathways that govern placental adaptive response to diverse stressors that adversely influence the balance between placental cell injury and repair. Primary areas of inquiry include: (1) the role of microRNAs in placental function, combining computationally identified sets of miRNA targets, RNAseq, and functional assays to decipher the critical role of unique placental microRNAs in response to cell injury, (2) microRNA packaging and trafficking within exosomes and other extracellular vesicles, and (3) placental lipotoxicity and mobilization of lipid derivatives that are critical for fetoplacental development.

Research at Magee-Womens Research Institute centers on reproductive biology and a range of health conditions that affect women, including fertility, development, pregnancy, genetics, infectious diseases, gynecology, cancer, and general women’s health.
 

This position will work standard working hours, daylight shifts, with the possibility of flexibility in the schedule. Hours are subject to change based on business needs.

 

This position is grant-funded.
 

Primary duties include overseeing lab operations, maintenance, purchasing, ordering, safety and compliance in the responsible conduct of research; overseeing and managing the laboratory’s specimen database and biobank; performing experiments that assist laboratory members in the conduct of molecular and cellular research projects; performing placental primary cell isolation and culture and assisting the Principal Investigator in the recruitment, orientation and monitoring of staff and students.


The Research Manager II manages the research laboratory within the laboratory and MWRI/MWH policies, procedures, and guidelines and according to applicable authority levels, laws, and regulations.

Responsibilities:

  • Receive limited advice and input as needed from the faculty supervisor.
  • Program complex scientific and mathematical problems for solutions on a computer.
  • Supervise library and computer search for research data.
  • May have responsibility for interviewing, orientation, scheduling, work assignment, and limited input as needed from a faculty supervisor.
  • Participate in planning and setting goals for the maintenance and development of activities and resources appropriate for the requirements of the laboratory.
  • Resolve unique problems by collecting and interpreting information.
  • The results of actions have a measurable impact on a faculty investigator's research operation. Individual's actions are limited to a single work area and would have a significant effect on the outcome of the research.
  • Ensure the operational efficiency and accuracy of laboratory equipment; arrange for the repair of equipment.
  • Prepare, monitor, and manage annual capital, labor, and operating laboratory budgets.
  • Participate in the preparation of papers for publication and presentation at meetings.
  • Implement, maintain, document, and assist in the development of an effective quality assurance/quality control program; meet reporting schedules and standards.
  • Organize and interpret data and report the results to the principal investigator, study nurses, and study monitors.
  • Develop and maintain an organizational plan for the laboratory.
  • Required to have an understanding of practices and procedures.
  • Perform complex scientific data reductions requiring the use of independent judgment.
  • Work with the principal investigator and study nurses to solve study protocol problems.
  • Solutions may include working with faculty supervisors to modify procedures and methods to address new conditions.
  • Ensure that the laboratory meets applicable department, hospital and regulatory safety and fire requirements.
  • Moderate interaction outside of own work area and the MWRI.
  • Write, update, and maintain the laboratory policy and procedure manual according to department and hospital standards.
  • Perform laboratory procedures and tests. Analyze and interpret the results.
  • Develop curriculum materials for an educational session(s).
  • Responsible for following the mandatory reporting procedures for any incident or serious event that did affect or potentially could have affected the clinical care of any patient.

 

Qualifications

  • Bachelor’s degree in Medical Technology, Chemistry, or Basic Science.
  • At least six years of post-graduate technical experience in a research environment.
  • At least 1-2 years in a supervisory capacity with a staff of at least 2 and responsibility over at least 2 extramural research studies.
  • Previous experience as a Research Assistant, Research Associate, and/or Laboratory Supervisor in a research environment.
  • Proficient management and analytical skills.
  • Excellent interpersonal and communication skills.
  • Demonstrated ability to handle, process, and evaluate specimens for testing.

 

Licensure, Certifications, and Clearances:

  • Act 34

UPMC is an equal opportunity employer. Minority/Females/Veterans/Individuals with Disabilities.

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