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Research Manager I

Description

UPMC Magee-Womens Research Institute is seeking a Full-time Research Manager I to support the Jasarevic Research Group department!

This position will work daylight shifts. Hours are subject to change based on business needs.

This position is grant-funded.

Parental lifetime experiences have a profound impact on the health of future generations. For instance, children of mothers who themselves experienced malnutrition or chronic stress are at significantly higher risk for poor health outcomes, including obesity, asthma and neurodevelopmental disorders, suggesting that trauma and adversity may be transferred from one generation to next. The Jašarević research group is a new hybrid wet/dry laboratory at the Magee-Womens Research Institute and University of Pittsburgh School of Medicine that is focused on mining the vastly unexplored wealth of immunomodulatory and metabolic activities in the maternal microbiota to identify novel mechanisms involved in this intergenerational transmission of health and disease. To this end, our research group applies an innovative and multidisciplinary approach that revolves around a unified vision: a bench-to-bedside-and-back approach that leverages clinical collaborations, translationally relevant models, and state-of-the-art tools to develop prognostic and therapeutic interventions that target modifiable components of the maternal microbiota to guide healthy development and prevent poor health outcomes in offspring.

We seek a Senior Research Associate with interest and excitement to help establish a brand new multi-disciplinary hybrid wet/dry lab focused on the role of the microbiome in health and disease. Additionally, the candidate should exhibit extensive experience with animal husbandry and expertise with colony maintenance techniques, including genetic crossing and molecular genotyping. A working knowledge and interest in next generation sequencing, flow cytometry and cell sorting are preferred. Familiarity with an automated liquid handler system is desired but not required. Additional duties and qualifications are listed below.

Manage research laboratory within laboratory and MWRI/MWH policies, procedures, and guidelines and according to applicable authority levels, laws and regulations.

Responsibilities:

  • The results of actions have a measurable impact on a faculty investigator's research operation.
  • Maintain animal husbandry, carrying out genetic crosses and molecular genotyping. Conduct assay development and experimental troubleshooting.
  • Assist with laboratory organization, including ordering of lab equipment, reagents, consumables.
  • Training new laboratory personnel in lab techniques.
  • Supervising graduate and undergraduate students in the lab.
  • Perform regular inventory management of laboratory equipment, reagents and supplies.
  • Ability to work independently and collaboratively as part of a dynamic team.
  • Required to understand practices and procedures. Resolve unique problems by collecting and interpreting information.
  • Perform complex scientific data reductions requiring the use of independent judgment.
  • Ensure that the laboratory meets applicable department, hospital and regulatory safety and fire requirements.
  • Implements, maintains, documents, and assists in the development of an effective quality assurance/quality control program; meets reporting schedules and standards.
  • Participate in the preparation of papers for publication and presentation at meetings.
  • Individual's actions are focused on a specific section of the lab work and would have a measurable effect on the outcome of the research.
  • Organizes and interprets data and reports the results to principal investigator, study nurses and study monitors.
  • Work with principal investigator and study nurses to solve study protocol problems.
  • Receive advice and input as needed from faculty supervisor. Write, update, and maintain the laboratory policy and procedure manual according to department and hospital standards.
  • Solution may include working with faculty supervisor to modify procedures and methods to address new conditions.
  • Ensure the operational efficiency and accuracy of laboratory equipment; arranges for the repair of equipment.
  • Assist with the development of curriculum materials for an educational research session(s).
  • May have responsibility for interviewing, orientation, scheduling, work assignment and receives input from faculty supervisor.
  • Program complex scientific and mathematical problems for solutions on a computer.
  • Supervise library and computer searches for research data.
  • Perform laboratory procedures and tests. Analyze and interpret the results.
  • Limited interaction outside of own work area and the MWRI.
  • Responsible for following the mandatory reporting procedures for any incident or serious event that did affect or potentially could have affected the clinical care of any patient.

Qualifications

  • Bachelor’s Degree in medical technology, chemistry, or basic science.
    • BA/BS/MS in biological science (e.g. molecular biology, immunology, genetic, bioengineering) or relevant disciplines, and equivalent experience HIGHLY preferred.
  • At least four years of post-graduate technical experience in a research environment.
  • Previous experience as a Research Assistant and/or Research Associate in a research environment.
  • Strong experience with mammalian cell culture, molecular biology, and flow cytometry preferred.
  • Working knowledge with next generation sequencing prep, flow cytometry, and cell sorting preferred.
  • Extensive experience with animal husbandry and colony maintenance and carrying out genetic crosses of mice to be confirmed by molecular genotyping preferred.
  • Experience with assay development and high throughput screening preferred.
  • Comfort working with rodent and human blood, feces, and vaginal secretions preferred.
  • Experience with immunology assays (e.g. intracellular cytokine assays, ELISPOT, phagocytosis) and live cell imaging preferred.
  • Familiarity with automated liquid handler system preferred.
  • Interest in joining a research group that seeks to apply bioinformatics and machine learning to women’s health preferred.
  • Proficient management and analytical skills.
  • Excellent interpersonal and communication skills.
  • Demonstrated ability to handle, process and evaluate specimens for testing.

Licensure, Certifications, and Clearances:

  • Act 34

UPMC is an equal opportunity employer. Minority/Females/Veterans/Individuals with Disabilities.

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   Current UPMC employees must apply in HR Direct