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Research Tech Clinical Research

Description

UPMC Magee-Womens Hospital is seeking a Full-time Research Tech Clinical Research to support the Liang: Tobacco 2021department!

This position will work Monday through Friday from approximately 9:00 a.m. to 5:00 p.m. Hours are subject to change based on business needs.

This position is grant-funded.
Under supervision, the Research Tech Clinical Research is responsible for accurately performing research projects according to established study design and procedures.

The goal of Dr. Artsen’s research is to improve current treatment paradigms of pelvic floor disorders by understanding the mechanisms behind vaginal mesh complications. Polypropylene mesh is frequently used to decrease failure rates of prolapse repairs and treat stress urinary incontinence but is associated with rates of pain and exposure into the vagina in up to 10% of cases. To date, little attention has been paid to the role of the host in the response to a urogynecologic mesh. Using mesh samples removed from women with complications, mouse models and innovative tissue-modeling systems, Dr. Artsen aims to test the role of dysregulated wound healing in mesh complications and to test the therapeutic utility of extracellular matrix-associated molecules in vaginal healing after mesh placement. Gaining an improved understanding of the host response to biomaterials used in reconstructive pelvic surgeries will open new potential therapeutic avenues and contribute to a future in which these complications are rare events. Experimental techniques to be used include but are not limited to breeding and assisting on surgery in mice, protein extraction and sample preparation, immunofluorescence, qPCR, and western blots.

The goal of Dr. Liang’s research is to investigate the mechanisms by which women with diabetes have increased risk of mesh-related complications following the implantation of urogynecologic mesh in the surgical repair of urinary incontinence and pelvic organ prolapse, thereby developing therapeutic approaches to improve the mesh outcomes in this cohort.  The job includes but is not limited to model maintenance, assisting in surgeries and euthanasia, tissue processing for histology and biochemistry, performing experiments by following protocols, cell culture maintenance and carrying out some administrative tasks. The research technician would spend 3 days a week on Dr. Liang’s projects and 2 days on Dr. Artsen’s projects.


Responsibilities:

  • Maintain a safe clean laboratory-working environment including appropriate equipment maintenance and usage, by conforming to laboratory and Hospital policies and standards.
  • Administer questionnaires and assist with procedures for obtaining patient screening and recruitment as well as obtaining research specimens.
  • Assist in performing research protocol experimental procedures, under close supervision, including appropriate collection, recording, storage and analysis of data.
  • Prepare, label, store and dispose of reagents and calibrates equipment for research projects.
  • Maintain laboratory inventory, including timely ordering and receipt of required supplies and their proper storage.
  • Assist in obtaining educational resources necessary to perform and interpret research and to remain abreast in research area of function.
  • Follow appropriate research policies and procedures including all applicable laws and regulations and maintain scientific integrity including accurate data storage.
  • Responsible for following the mandatory reporting procedures for any incident or serious event that did affect or potentially could have affected the clinical care of any patient.

Qualifications

  • High school diploma or equivalent.
  • One year of college training or one year of experience working within a biomedical research laboratory environment.
  • Demonstrated ability to accurately collect, store and interpret research data.
  • Demonstrated ability to communicate with patients, staff, and investigators.

Licensure, Certifications, and Clearances:

  • None

UPMC is an equal opportunity employer. Minority/Females/Veterans/Individuals with Disabilities.

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   Current UPMC employees must apply in HR Direct