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UPMC complies with all governmental requirements related to local, state, and federal COVID-19 vaccination for employment. The Jan. 13 Supreme Court of the United States decision that the Centers for Medicare & Medicaid Services federal COVID-19 vaccine mandate will move forward requires UPMC to ensure employees either get vaccinated or receive a requested medical or religious exemption.

If you are not yet vaccinated, we urge you to get a vaccine now. You can schedule your COVID-19 vaccination through UPMC or visit a non-UPMC provider or UPMC Urgent Care location.

Proof of vaccination is not required upon hire; however, employees will be responsible for ensuring post-hire compliance by getting vaccinated or requesting a medical or religious exemption.

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   Current UPMC employees must apply in HR Direct

Molecular Genomic Specialist I or II

  • Job ID: 247130712
  • Status: Full-Time
  • Regular/Temporary: Regular
  • Hours: Monday - Friday daylight shifts
  • Shift: Day Job
  • Facility: University of Pittsburgh Physicians
  • Department: Clinical Genomics
  • Location: 5230 Centre Avenue, Pittsburgh PA 15232
  • Union Position: No
  • Salary Range: $26.14 to $42.84 / hour


UPMC Genome Center is hiring a Molecular Genomic Specialist (I or II) to support the Clinical Genomics Lab. This role is Monday - Friday daylight shifts. The role will rotate through sample accessioning, DNA/RNA extraction, library preparation, and sequencing benches. The staff member will complete basic inventory tracking, reagent tracking, quality management, and sample tracking in LIMS system as part of the hands-on wet bench work.
Our department offers the opportunity to learn clinical next generation sequencing assays and high-throughput pharmacogenetics. We are a complex clinical lab, with lots of variation in the day-to-day routine.

 Why UPMC?

We don't just take care of our patients - we take care of our team too. In addition to our competitive benefits package, you can expect:

  • A generous sign-on bonus of $15,000 for those who qualify.
  • A challenging and rewarding career that provides a wide variety of job responsibilities as well as opportunities to identify and build upon individual strengths.
  • Lab-wide collaboration and teamwork where each staff member is valued for their unique skill set that they can offer to the team.
  • A career ladder that provides growth opportunities for lab associates to enjoy more professional challenges, promotional opportunities, and career enhancement.
    • UPMC was ranked #1 for "Best Places to Work for Women & Diverse Managers" by Diversity MBA Magazine’s: 50 Out Front Companies for two years in a row.
    • U.S. News & World Report consistently ranks UPMC Presbyterian Shadyside among the nation’s best hospitals in many specialties.
      • It is ranked #1 in Pittsburgh and #2 in Pennsylvania.

Applicants will be placed into the appropriate job title and salary based on their individual experience and education. The Molecular Genomic Specialist I salary starts at $23.82/hr.

Sign on bonus may be available 


  • Train new lab members.
  • Accurately record relevant data and values in case folders and internal databases.
  • Demonstrate high-level problem-solving skills and analytical abilities to successfully perform laboratory testing.
  • Independently perform clinical testing in accordance with established SOPs. Process all clinical, QC and PT specimens through clinical workflow.
  • Accurately and precisely analyze molecular assay results for final interpretation by medical staff.
  • Maintain track of technical and professional development, including but not limited to attendance at seminars/webinars and participation in educational programs and activities.
  • Appropriately use automated and/or liquid handling machines for clinical testing.
  • Process samples meticulously to avoid cross-contamination.
  • Adhere to established laboratory and hospital policies and good clinical laboratory practice in areas of procedures, quality control, quality assurance and safety and compliance.
  • Assist in research projects, new assay development and/or document control review as requested.
  • Operate, perform routine maintenance on, and calibrate all laboratory equipment as required.
  • Maintain expertise in or knowledge of molecular biology techniques, including but not limited to: nucleic acid isolation, nucleic acid quantitation, PCR/RT-PCR/qPCR, Sanger sequencing, LOH, methylation analysis, MassARRAY MALDI-TOF, next-generation sequencing, etc.
  • Identify problems with instrumentation, methodology, specimens, and/or supplies and follow-up according to established protocols.
  • Help with instrument maintenance / PM.
  • Identify critical, abnormal and/or unacceptable results and follow-up according to established protocol.
  • Maintain supply inventory and order new supplies when needed.
  • Meet established turn-around-time deadlines for clinical testing.
  • Document all corrective action and follow-up with lead and/or supervisor.
  • Maintain proficiency in appropriate Laboratory Information Management Systems (LIMS).
  • Effectively communicate with other laboratory members including lab leadership.



Molecular Genomic Specialist I: Please upload your transcripts 

  • BS degree, major in biological science field OR; 
  • BS degree in chemical or physical science field with at least 1 year of experience in clinical molecular laboratory AND 16 semester hours in chemistry (including at least 6 hours in inorganic chemistry), 16 semester hours in biology courses pertinent to the medical sciences, and 3 semester hours in mathematics.
  • One (1) year of clinical molecular laboratory experience OR 1 year of experience through training in appropriate molecular laboratory coursework.

Molecular Genomic Specialist II:

  • BS degree, major in biological science field OR;
  • BS degree in chemical or physical science field with at least 16 semester hours in chemistry (including at least 6 hours in inorganic chemistry), 16 semester hours in biology courses pertinent to the medical sciences, and 3 semester hours in mathematics.
  • At least 3 years of molecular laboratory experience.

Preferred Experience

  •  PCR, Molecular, NGS (next generation library prep) experience
  • Can pipette; has sequencing, Chemagic-360, or molecular experience; has experience troubleshooting and/or optimizing molecular assays

Licensure, Certifications, and Clearances:
(MB) ASCP certification preferred.

  • Act 34

UPMC is an Equal Opportunity Employer/Disability/Veteran


COVID-19 Vaccination Information

Individuals hired into this role must comply with UPMC’s COVID vaccination requirements upon beginning employment with UPMC. Refer to the COVID-19 Vaccination Information section at the top of this page to learn more.

UPMC has a Center for Engagement and Inclusion that is charged with executing leading-edge and next-generation diversity strategies to advance the organization’s diversity management capability and its national presence as a diversity leader. This includes having Employee Resource Groups, such as PRIDE Health or UPMC ENABLED (Empowering Abilities and Leveraging Differences) Network, which support the implementation of our diversity strategy.

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   Current UPMC employees must apply in HR Direct